CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization
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چکیده
منابع مشابه
Association between choroidal morphology and anti-vascular endothelial growth factor treatment outcome in myopic choroidal neovascularization.
PURPOSE To investigate associations between outcome of anti-vascular endothelial growth factor (VEGF) therapy and choroidal morphology in eyes with myopic choroidal neovascularization (CNV). METHODS Fifty-two eyes of 46 patients with myopic CNV received a single intravitreal anti-VEGF injection, followed by as-needed injections. Baseline choroidal thickness was measured at the fovea and 1.5 a...
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Myopic choroidal neovascularization (CNV) is one of the most vision-impairing complications in patients with pathologic myopia. It is also one of the most frequently encountered non.age-related macular degeneration causes of CNV and affects young patients in the working age group. Fluorescein angiography (FA) and spectral domain optical coherence tomography (OCT) are generally indicated to conf...
متن کاملChoroidal neovascularization in eyes with choroidal vascular hyperpermeability.
PURPOSE We describe the clinical and genetic characteristics of choroidal neovascularization (CNV) in eyes with choroidal vascular hyperpermeability (CVH). METHODS This cross-sectional study consisted of 438 consecutive patients who underwent fluorescein and indocyanine green angiography for macular disease. We used the genotypes of 1576 age-related macular degeneration (AMD) cases and 3248 g...
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PURPOSE Dendritic cells (DCs) are innate immune cells that have recently been shown to support angiogenesis in tumors, endometriosis, and lymph nodes. A major cause of legal blindness is wet age-related macular degeneration (wet ARMD), wherein abnormal blood vessels grow under the retina, an abnormality also referred to as choroidal neovascularization (CNV). The purpose of the present study was...
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This study was designed to evaluate the inhibitory effect of endostatin on choroidal neovascularization (CNV) in laser-induced rat model. Choroidal neovascularization was induced in Brown Norway (BN) rats by diode-laser photocoagulation. Rats were randomly divided into five groups (10 animals in each group): endostatin 20mg/kg group, endostatin 10mg/kg group, laser injury group, normal saline g...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2021
ISSN: 1552-5783
DOI: 10.1167/iovs.62.3.37